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For a lupus patient whose hsCRP runs chronically elevated, this kind of reduction could meaningfully affect disease trajectory
But theyre struggling with it. For example, when writer Elna Baker lost 110 pounds, she got a lot of attention and affirmation but it felt flimsy
Guidelines Exclusion Criteria Exclusion Criteria If present, the following indicate that the client should not receive tirzepatide (1-5): Diagnosis of Type I diabetes Personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 Severe gastrointestinal dysmotility History of pancreatitis Pregnancy Proliferative Diabetic Retinopathy (PDR), severe Nonproliferative Diabetic Retinopathy (NDR), clinically significant myalgic encephalomyelitis (ME), or diabetic macular edema (DME) unless the risks and benefits have been discussed with the client and are documented in the clients health record along with monitoring plans and follow-up with an eye specialist who is informed at the time of initiation
PMID:1397775
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