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But Health Canada says on its website that DHEA, also known as prasterone, "can cause higher than normal levels of female and male hormones in the body and could increase the risk of prostate, breast, ovarian, and other hormone-sensitive cancers." "There are no medications authorized for use in Canada that contain prasterone [DHEA]," Sean Upton, senior media relations officer at Health Canada, told the fifth estate in an email

A key issue is the overlapping substrate specificity among enzyme families, which can lead to off-target responses

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In powder form, retatrutide can be stored at minus 20 degrees Celsius (minus 4 degrees Fahrenheit) for extended periods, making it suitable for bulk purchasing