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The medication is metabolised in the liver and excreted primarily through the kidneys
This approach could theoretically prevent Cas9 DNA integration into the host genome, thereby reducing the risk of unintended off-target effects and further enhancing the safety of LNP-based in vivo genome editing
Adults can synthesize sufficient L-carnitine to maintain normal metabolic levels, but infants have a weaker synthetic capacity, only about 12-15% of that of adults
Mounjaro is available only by prescription and requires a medical evaluation
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