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Similarly, several novel MCT1/4 inhibitors are under investigation, including AZD3965, which has demonstrated anti-tumor effects by inhibiting MCT1, disrupting lactate metabolism in tumors, and causing lactate accumulation within cancer cells
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TMAO has been proven to aggravate CVD by promoting atherosclerosis and thrombotic risk and has also been reported to be correlated with other cardiometabolic diseases such as non-alcoholic fatty liver disease and chronic renal disease [6,7,8]
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