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During a mean follow-up of 7.4 years, there was a significant 12% reduction in the primary efficacy endpoint but an increase in major bleeding events in the aspirin group, where most cases were gastrointestinal and others extracranial bleeding

Mean weight loss -20.4% vs -3.0% placebo

The dataset included formal low blood pressure diagnoses, systolic blood pressure readings dropping below 90 mm Hg, new prescriptions for hypotension drugs, and sudden episodes of dizziness, lightheadedness, fainting, and physical falls