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Mechanism of action : Prescription GLP-1 receptor agonists work by directly binding to and activating GLP-1 receptors throughout the body, producing robust and predictable effects on insulin secretion, glucagon suppression, gastric emptying, and appetite
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One theory is that the inhibition by GLP-1 is normally exerted indirectly via paracrine somatostatin secretion, which markedly diminishes during hypoglycaemia [66]
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