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Trends in Food Science & Technology, 118:735-743
Those with symptomatic gallstone diseasepain, nausea, or recurrent episodesshould either have the gallbladder removed before starting GLP-1 therapy or pursue non-surgical weight loss methods
The STEP trials allowed ondansetron (Zofran) 4 mg as rescue medication, and real-world data suggests 15% to 20% of patients benefit from intermittent antiemetic use during the dose-escalation phase
The FDA-mandated minimum is 72 hours (three days)
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