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The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking
Allergic Reactions: On rare occasions, an individual might have an allergic reaction to the shot
Nature Reviews Molecular Cell Biology (2021) 10
In this way AngIV may act in combination with AT 1 receptor blockade to protect DA neurons
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