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If you are considering starting B12 supplements, particularly at high doses, discuss this with your GP or a registered pharmacist, especially if you have existing medical conditions or take other medications
The compounds effects on NAD+ metabolism may have implications for muscle biology given the importance of NAD+-dependent enzymes in muscle function
Take them 30 to 60 minutes before bed
At the 2.4mg maintenance dose, a 10mg vial lasts only 4.16 weeks, which aligns almost perfectly with the 28-day reconstitution window
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