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The role of other mediators of the anorexigenic pathway is shown in Figure 1.0 Figure 1.0 Schematic diagram of both orexigenic and anorexigenic pathways

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In a typical encapsulation experiment, PLGA nanoparticles exhibited a hydrodynamic diameter of 170 30 nm (z-average, PDI = 0.162) as measured using dynamic light scattering with anionic effective surface charge (20.5 5.3 mV) due to the terminal carboxylate groups on the PLGA polymers

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