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Description

MGF (Mechano Growth Factor) is a splice variant of the IGF-1 gene expressed in mechanically stressed muscle tissue

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Tirzepatide builds upon this foundation by also activating the GIP receptor

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IL-11R-targeted polymersomes encapsulating doxorubicin (IL11-PDox) demonstrated significantly augmented internalization and apoptotic activity in IL-11R-overexpressing osteosarcoma cells, leading to striking repression of tumor growth and lung metastasis in orthotopic and relapsed models (60)

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