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That means that a big open question is whether the side effect profiles may differ in subgroups of people that scientists have not directly studied, which include a large swath of people now taking these drugs to lose only about 10 to 15 pounds
A 2025 clinical trial published in JAMA Psychiatry found significant reductions in drinking among participants taking semaglutide
In February 2016, Pax Jones, an activist and photographer based in Texas, woke up to find that photos she had taken of her Sri Lankan classmates showing dark-skinned beauty, and tagged with #UnfairandLovely, had gone viral (the tag is a play on one of South Asias most renowned skin-lightening creams, Fair and Lovely)
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