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Furthermore, although all GLP-1RAs carry the potential for causing DR secondary to rapid glucose lowering, observations of new or worsening DR within primary literature thus far have been isolated to the SUSTAIN-6 trial
Sitagliptin was modestly removed by hemodialysis (13.5% over a 3- to 4-hour hemodialysis session starting 4 hours postdose)
TB-500 contributes systemic anti-inflammatory effects that may benefit inflammatory bowel conditions, though its primary value lies in tissue applications beyond the gut
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