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Traditional methods have typically included high performance liquid chromatographic assays and are characterized by underestimation of GSH and overestimation of GSSG due to the autooxidative properties of GSH (Nuhu et al., 2020)

PMID: 33711021 Keywords Alpha Sympathomimetics Brimonidine Trade Names: Alphagan-P, Qoliana, Lumify & generic FDA approved in 1996 Drug Class: Alpha-2 Selective Adrenergic Agonist, Antiglaucoma, Vascular decongestant Mechanism of Action: 2 adrenoreceptor agonist approximately 10-times more selective for alpha-2 receptors compared to clonidine (Cambridge, 1981) does not exhibit significant tachyphylaxis with repeated use (Lee & Kim, 2022) Indications: Prescription & OTC to treat symptoms of: open-angle glaucoma : to lower intraocular pressure or ocular hypertension (Alphagan-P, Qoliana )

This project is supported by the Grant of National Natural Science Fund of China (Grant no.82250410378), Zhenjiang key research and development plan (social development) (Grant no

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