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One study has indicated that after 16 weeks of treatment, on average, people lose 5.7% of their body weight and a separate study has shown that after a period of 68 weeks, there is an average of 15% of body weight lost
In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo
Some of the significant GLP-1R agonists studied other than semaglutide are liraglutide and exendin-4
The GLP-1R/GIPR dual-agonist tirzepatide has demonstrated a remarkable 23% body weight reduction in individuals with obesity over 72 weeks, eclipsing the average result achieved by certain bariatric surgery [78]
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