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intestine and renal MDA, TNF-, IL-6, caspase 3 & 8, and histopathological modifications
For weight management , NICE technology appraisal guidance supports semaglutide 2.4 mg (Wegovy) for adults with at least one weight-related comorbidity and a BMI 35 kg/m (or 30 kg/m in exceptional circumstances), as part of a specialist weight management service
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Slow dose escalation improves tolerance and minimizes the potential risks
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