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This regulatory gap means that patients may be taking supplements of uncertain composition alongside a potent investigational drug
Patients entered a run-in treatment period on glimepiride (4 mg per day) alone or glimepiride in combination with metformin HCl (1500 mg per day)
However, responsibility dictates that such combinations remain firmly within the realm of controlled, scientific investigation until robust evidence supports their safety and efficacy
Because GLP-1 agonists slow gastric emptying, the post says post-bypass patients may experience worsening dumping syndrome symptoms, and it calls for pre-treatment assessment of that history
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