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However, we found a significant risk of developing NAION with semaglutide," Fernando Gerchman, MD, PhD, and coauthor of the study, said in a statement to The American Journal of Managed Care

For mood, the FDA has been investigating reports of suicidal ideation and mood changes on GLP-1 medications, though the 2024 EMA review and ongoing FDA analyses have not found a causal link

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