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Moreover, TB-500 also appeared to have promoted the expression of CD31, -smooth muscle actin (-SMA), Ang2, tie2, VEGFA, N1ICD, and p-p65 in the muscle tissues of murine CLI models
Shineman DW, Salthouse TA, Launer LJ, et al
Utomo A, Jiang X, Furuta S, Yun J, Levin DS, Wang YC, Desai KV, Green JE, Chen PL, Lee WH
Mechanistically, DMSO is a cell-permeable reagent known to bind to various proteins in the cytoplasm or nucleus 8 , which directly (chemically and physically) interrupts their functions 9
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