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Dapagliflozin in patients with heart failure and reduced ejection fraction
The most important risk factor is concomitant use of insulin or insulin secretagogues (sulfonylureas such as glipizide, glyburide, or glimepiride, and meglitinides such as repaglinide)
however, in combination with 0.01 M MTX was significantly able to reduce cell viability
Terpstra M, Vaughan TJ, Ugurbil K, Lim KO, Schulz SC, Gruetter R
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