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These include: Inappropriate dosing or frequency Lack of proper diagnosis and monitoring Non-sterile injection technique increasing infection risk Absence of medical supervision for adverse reactions Financial cost without clinical benefit Patients should report any suspected adverse reactions to B12 injections via the MHRA Yellow Card scheme
Presented for research literature review only Denu JM (2007)
It allows for more accurate study design, as you can be more confident in the actual amount of the compound interacting with target tissues
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