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While DHAR1 has been localized to the peroxisomes, DHAR2 is cytosolic and DHAR3 encodes a dual-addressed chloroplast/mitochondrial enzyme (Figure 2)

On the other hand, several GPs that had no significant fold change at the end of 4th week during 4-week intermittent fasting compared with the levels before 4-week intermittent fasting, had a significant fold change 1 week after 4-week intermittent fasting compared with the levels at the end of 4th week during 4-week intermittent fasting (e.g., PRKCSH, HIST1H2BA) (Table 2)