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January 30, 2026: FDA Approves Labeling Update for Rybelsus (Semaglutide) Tablets The FDA has updated the label for Rybelsus, a semaglutide pill prescribed for diabetes management and other approved uses

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[16] Shilajit Shilajit is a natural substance found primarily in the Himalayas, formed over centuries by the decomposition of plant matter

This slowing contributes to the appetite suppression that drives weight loss and the postprandial glucose-lowering effect, and it also drives most of the gastrointestinal side effect profile.[1],[2] A 2025 review in the Journal of Clinical Endocrinology & Metabolism summarizes the published evidence: GLP-1 receptor agonists impact gastric, intestinal, and gallbladder motility simultaneously, with effects on gastric fundus relaxation, antral contractility inhibition, increased pyloric tone, and reduced small intestinal motility.[3] The path from this mechanism to constipation is straightforward