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To further ensure safety during RT in older adults, prescribing machine-based exercise early on in programming as opposed to free-weights is an ideal alternative that typically will protect the lower back by avoiding spinal loading and compensatory movements through the back, and allow for greater control and balance during exercise with external load (Feigenbaum and Pollock, 1999)
Moreover, intracellular C5aR1 has been reported to interact with KCTD5/Cullin3/Roc1/-catenin to form a stable complex, thereby increasing the stability of -catenin and promoting the occurrence of colorectal cancer [32]
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