Ipamorelin, a pentapeptide ghrelin mimetic, binds to ghrelin receptors (GHS-R1a) on the same somatotrophs, synergizing with Tesamorelin to amplify GH release without stimulating ACTH or cortisol secretion the way earlier secretagogues like GHRP-6 did
However, the International Peptide Society has published two epithalon dosing protocols based on the extensive work of Professor Khavinson and colleagues
Aroda, MD, and Melanie Davies, CBE, MBChB, MD, FRCP, FRCGP, FMedSci, will review the latest data for a novel oral glucagon-like peptide-1 receptor agonist in people living with with type 2 diabetes or overweight or obesity
TRANSCEND-T2D-1 reported results on March 19, 2026 the first Phase 3 diabetes readout: These trials are expected to further broaden retatrutide's potential label across metabolic, musculoskeletal, and liver disease indications