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Still, the studys scale, duration and granular clinical data provide meaningful evidence to inform riskbenefit discussions. Balancing risks and benefits Importantly, the analysis assessed risk associated with initiation of semaglutide rather than cumulative dose or treatment duration. Whether risk varies by dosing intensity or length of exposure remains an open question
Tirzepatide pushed that figure to approximately 20-22%
It reflects a normal physiological response to weight loss
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