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For participants assigned to receive doses of 4 mg or higher, treatment was initiated at a lower dose of either 2 mg or 4 mg, followed by gradual dose escalation every four weeks for up to 12 weeks
[7] [13] It has a half-life of approximately five days that supports weekly dosing
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These are a set of guidelines designed to ensure the quality, consistency, and reliability of non-clinical safety tests, from their inception to the recording and reporting of results
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