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Treatment with GLP-1RAs can reduce monocyte/macrophage accumulation in the arterial wall by inhibiting the adhesion of monocytes to activated endothelium from the arteries of C57BL/6 mice as well as in ApoE -/- mice [64]

The remaining subclusters, -1, -1, and -2, were located in the middle of the trajectory (Figure 3E), suggesting that these subclusters maintain a more flexible cell identity

The medications have been shown to work most effectively when people are at their top doses for many months

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