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Stacey SK et al
Activation of this pathway destroyed the expression of tight junction proteins such as zonula occludens-2 (ZO-2), occludin, and vascular endothelial cadherin (VE-cadherin) in endothelial cells, which increased endothelial cell permeability
Deficiency Symptoms Men and women fed intravenously (IV) with solutions that contained adequate methionine and folate but lacked choline have been found to develop a condition called nonalcoholic fatty liver disease (NAFLD) and signs of liver damage that resolved when choline was provided (12)
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