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Researchers comment that a single introduction of the peptide may upregulate growth hormone production by somatotrophs for prolonged periods of time, thus apparently contributing to an overall increase in [growth hormone] secretion by 46% and also potentially upregulating its main anabolic mediator insulin-like growth factor-1 (IGF-1) by 45% on average

The device targets the dermis and subcutaneous layers without damaging the surface, making it safe and effective

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Published trials showed that the treatment with GLP1-RA reduced the risk of MACE and slowed the development of albuminuria in diabetic patients, demonstrating a direct cardio and reno-protective action of GLP1-RA, regardless the effect on glycemic control (60, 61)