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Similarly, the FDA has approved a number of injectable GLP-1s for type 2 diabetes, such as Ozempic (semaglutide), Mounjaro (tirzepatide), and (semaglutide), an oral GLP-1 medication for blood sugar control in people with type 2 diabetes
89 As a result, the transcription of genes promoting cell proliferation and survival is inhibited, while apoptosis-related genes may be upregulated
The FXR-FGF15/19 and FXR-SHP pathways are critical for maintaining metabolic homeostasis
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