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As there is some reserve there, some loss of lean mass is expected
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In the meantime, the addition of a choline supplement to the successful micronutrient cocktail is judicious, and probably should take precedence over calls to prescribe zinc, folate or magnesium
Whether the breadth translates to clinical benefit on intact human skin depends entirely on whether the molecule reaches the cells whose gene expression it modulates
However, additional precautions may be recommended for patients with significant gastrointestinal symptoms, recent dose escalation, or gastroparesis
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