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ER signaling has been associated with several potential therapeutic benefits in CNS disorders: (1) it enhances GABAergic over glutamatergic signaling, exerting anticonvulsant effects (Veliskova and Desantis, 2013)
The novel peptides ICRD and LCGEC screened from tuna roe show antioxidative activity via Keap1/Nrf2-ARE pathway regulation and gut microbiota modulation
Popular treatments approved by the FDA include Sales for Lillys GLP-1 treatments reached $40 billion in 2025, accounting for 62% of the companys annual revenue
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