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conducted a subgroup analysis of the Qatar study, an open-label, randomized controlled trial (62), and compared the peripheral neurological outcomes in patients receiving a combination of exenatide (2 mg/week) and pioglitazone (30 mg/day) and those receiving glargine plus aspart insulin (58)
This study included randomized clinical trials that evaluated the cardiometabolic effectiveness and safety of the combination therapy of SGLT-2i and GLP-1RAs versus monotherapy with either SGLT-2i, GLP-1RA, or treatment as usual (TAU) in adults ( 18 years) with T2DM
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