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Because MOTS-c enhances insulin-independent glucose uptake, patients with type 1 diabetes or those using exogenous insulin should be monitored carefully to prevent hypoglycemia, though this theoretical risk has not materialized in clinical reports to date
The subcutaneous layer is thicker in people who have more body fat and therefore patients with a higher BMI may need a longer needle to adequately get into the skeletal muscle
Rather than scar tissue limiting movement and function after an injury, TB-500 promotes the formation of healthy, flexible tissue
Potency decreases over time even under optimal storage
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