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2 Shanghai Key Laboratory of Vascular Lesions Regulation and Remodeling, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, Peoples Republic of China *These authors contributed equally to this work Correspondence: Ligang Zhou Department of Endocrinology, Shanghai Pudong Hospital, Fudan University, Shanghai, 201399, Peoples Republic of China Tel +8613611927616 Email [email protected] Abstract: GLP-1 receptor agonists (GLP-1RAs) and SGLT-2 inhibitors (SGLT-2is) are novel antidiabetic medications associated with considerable cardiovascular benefits therapying treatment of diabetic patients

Compounding pharmacies may add pyridoxine (if recommended by the healthcare provider) to semaglutide to possibly reduce the intensity and severity of gastrointestinal side effects

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