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Research suggests that the incidence of POI may be caused by premature primordial follicle activation, increased activation rate of primordial follicles, follicular maturation inhibition, or apoptosis acceleration [94, 222]
A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of research [PMID: 26330291] Laboratory literature summary: A Nampt inhibitor FK866 mimics vitamin B3 deficiency by causing senescence of research subjects fibroblastic Hs68 cells via attenuation
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They are often combined for a synergistic effect
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