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FOXO4-DRI theoretically has higher selectivity by targeting the FOXO4-p53 interaction that is specifically elevated in senescent cells
doi: 10.1039/D2BM01915A 21 LanY.ZhouJ.XuK
Their Glyteine is now available in the consumer-facing product Continual-G and is sold online in the US
However, patients should be aware of potential side effects: Bruising at IV site: Minor and resolves within days most common side effect Cool sensation: Fluids at room temperature may feel cool entering the bloodstream Metallic taste: Some nutrients (particularly zinc and magnesium) cause transient taste sensation Flushing/warmth: NAD+ and niacin-containing drips may cause temporary facial flushing Nausea: Rare usually indicates infusion rate is too fast (nurse will slow it down) Allergic reaction: Very rare nurse carries emergency supplies and monitors throughout The risk of adverse events increases significantly when IV drips are administered without medical oversight, by unqualified staff, or in non-sterile environments
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