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Tariffs on imported active pharmaceutical ingredients (APIs) or components used in the manufacturing of GLP-1 receptor agonists could potentially increase production costs for US-based manufacturers
These results indicate that the increased amount of non-12-OH FXR-antagonistic BAs consequent to the decrease in CYP8B1 expression after T3 treatment potentiates GLP-1 production by deactivating the intestinal FXR, thereby improving glucose homeostasis via the augmentation of insulin secretion
Updated January 5, 2015
UV spectrum of TPE-DCV in the detection medium shows an absorption band at 409 nm (Figure S5)
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