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Altering the PUFA composition of dopaminergic neuronal membranes and co-treating with iron can synergistically amplify lipid peroxidation and trigger ferroptosis, which has been confirmed in LUHMES cell and mouse organotypic brain slice experiments (70)
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El-Agroudy NN, Kurzbach A, Rodionov RN, OSullivan J, Roden M, Birkenfeld AL, et al
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