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35(4): 4827 Ross NS, Hoppel CL

Across the 52 weeks of ATTAIN-MAINTAIN, participants treated with orforglipron gained an average of 5 kg (11 lbs) in the tirzpatide group and an average of 1 kg (2.2 lbs) in the semaglutide group

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after 12 months of supplementing with 1,860 mg EPA plus 1,500 mg DHA, improvements in verbal fluency, language, memory, and visual-motor coordination were found, and these improvements persisted until the end of the trial at 30 months