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They are significantly larger than the molecules in a typical nicotine or birth control patch, making it very difficult for them to pass through the skin's protective outer layer and into the bloodstream in a therapeutic dose
However, as of March 2026, Hers claims it has shifted its focus to FDA-approved weight-loss treatments, limiting compounded semaglutide to medical necessity
According to a publication in Reviews in Endocrine & Metabolic Disorders, semaglutide is a well-tolerated and risk-free drug that has been demonstrated to have the ability to manage type 2 diabetes and obesity
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