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Moreover, a prospective cohort study including 18,961 subjects reported in the year 2022 that a 5-year increase in the duration of diabetes resulted in an excess risk of approximately 20% for CVD and stroke [9]

Treatment for confirmed B12 deficiency includes oral cyanocobalamin for dietary causes or intramuscular hydroxocobalamin for malabsorption or neurological involvement, following NHS and BNF guidance

Reducing caffeine and high-fat foods might help alleviate this symptom

21 Alpha-lipoic acid is a multifunctional compound in its ability to serve as a direct scavenger of free radical species and to also help in the regeneration of endogenous antioxidants such as glutathione 21 Supplementing with vitamin C has been shown to increase glutathione levels by exerting their antioxidant action first, thus sparing glutathione