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Calcium regulation of neuronal gene expression
However, 2D models fail to mimic the main ECM where ECs grow in vivo and the development of the glycocalyx is unknown in this type of culture [87]
H&E staining results further confirmed that the aortic wall thickness of mice treated with FOXO4-DRI was significantly thinner, and ultrasound examination results showed that the PWV of the aorta was slowed down after FOXO4-DRI treatment, indicating better vascular elasticity and significantly improved vascular function compared to the control group (Figures 2D,E)
Such findings suggest a possible role in maintaining circulation during tissue damage
