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While brand-name semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro) face ongoing supply constraints, compounded versions dispensed by licensed 503A compounding pharmacies remain a stable, regulated option for weight loss treatment
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Comparison with Metformin and SGLT2 Inhibitors Metformin: Often a first-line diabetes drug, but less effective for weight loss
These forces intensify during menopause, when shifting hormones drive stubborn weight gain around the midsection that diet and exercise alone rarely resolve
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