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On univariate analysis, maximum clot firmness (MCF) using both EXTEM and INTEM tests was significantly reduced in patients who had a bleeding event, compared to those who did not (50mm vs 57mm, p 2.8 m/sec
It promotes healing by upregulating growth factors, stimulating angiogenesis (new blood vessel formation), and enhancing collagen synthesis
Dosing & Reconstitution Guide Educational guide for reconstitution and daily dosing Standard / Gradual Approach (2 mL = 300 mg/mL) Frequency: Inject once daily subcutaneously, or split into every-other-day dosing based on protocol goals [5]
N Engl J Med 384(12):11361143
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