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755 Mechanistically, SSAT1 overexpression increases ALOX15 expression and decreases the expression levels of GPX4 and SLC7A11 in primary cortical neurons, suggesting that SSAT1/ALOX15 axis activation may aggravate brain I/R injury by triggering ferroptosis in neurons

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For instance, individuals with Class 3 obesity were 2.1 times more likely to receive a first-time T2D diagnosis and 3.2 times more likely to receive a sleep apnea diagnosis compared to those with overweight

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