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In PDB ID 1nu8, Diprotin A forms a tetrahedral intermediate, where the C atom of the carbonyl group of Pro2 in Diprotin A was found in a tetrahedral configuration (grey ball in Figure 5) covalently linked to Ser630

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Glucagon-like Peptide-1 Receptor Agonists and Muscle Mass Effects. Pharmacological Research , vol

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All of the residues involved in forming the complex are strictly conserved in mammals, subsequently underlining their essential role in catalysis

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