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They also alter the energy storage balance in the brain, making it easier to lose weight, says Megahan Garcia-Webb, MD, a triple board-certified physician specializing in obesity medicine and producer of the YouTube series Weight Medicine with Dr

The Big factor: How Quickly the Dose Reaches an Effective Level Because it reaches its target dose sooner, some people may see earlier scale movement, but average total weight loss tends to be more modest than newer agents

Prioritizing protein also extends satiety between meals, counteracting the reduced appetite even further and helping you stick to smaller portions without feeling deprived