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This increased oxygen consumption leads to the production of more free radicals and oxidative stress, which causes damage to cells and tissues
High oxidative stress may lead to hyperpigmentation or dullness of the skin
Levamisole, a therapeutic agent that specifically targets CD133, a recognized marker of OCSCs, has been developed (67)
The removal efficiency in these systems is typically between 50% and 90%, depending on the sludge retention time, hydraulic loading, and particle size distribution [54,55]
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